A10G (p.Ala10Gly) variant of CYP2D6 (Cytochrome P450 2D6)
A10G (p.Ala10Gly) in CYP2D6 (Cytochrome P450 2D6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes population frequency data and structural context.
A10G (p.Ala10Gly) variant details
- p.Ala10Gly
- gnomAD rs1447119000
- Missense
- Variant Prioritization Score for Impact Estimate 0.425
- CADD 14.50
- PolyPhen-2 0.01
- SIFT 0.19
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available