W20C (p.Trp20Cys) variant of CYP2C9 (Cytochrome P450 2C9)
W20C (p.Trp20Cys) in CYP2C9 (Cytochrome P450 2C9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.46 / 1. The record also includes population frequency data and structural context.
W20C (p.Trp20Cys) variant details
- p.Trp20Cys
- 1000Genomes rs533309841
- ExAC rs533309841
- TOPMed rs533309841
- gnomAD rs533309841
- Missense
- Variant Prioritization Score for Impact Estimate 0.461
- REVEL 0.35
- CADD 23.40
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 5.9e-05)
- Structural context available