V64L (p.Val64Leu) variant of CYP2C9 (Cytochrome P450 2C9)
V64L (p.Val64Leu) in CYP2C9 (Cytochrome P450 2C9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.47 / 1. The record also includes population frequency data, published literature, and structural context.
V64L (p.Val64Leu) variant details
- p.Val64Leu
- gnomAD 10-94941879-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.466
- REVEL 0.41
- CADD 19.10
- PolyPhen-2 0.37
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available