V5M (p.Val5Met) variant of CYP2C9 (Cytochrome P450 2C9)
V5M (p.Val5Met) in CYP2C9 (Cytochrome P450 2C9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data, published literature, and structural context.
V5M (p.Val5Met) variant details
- p.Val5Met
- gnomAD 10-94938695-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.263
- REVEL 0.11
- MetaLR 0.15
- MetaSVM -0.98
- CADD 11.40
- PolyPhen-2 0.04
- SIFT 0.21
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available
- Literature evidence available