V5L (p.Val5Leu) variant of CYP2C9 (Cytochrome P450 2C9)
V5L (p.Val5Leu) in CYP2C9 (Cytochrome P450 2C9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data and structural context.
V5L (p.Val5Leu) variant details
- p.Val5Leu
- gnomAD rs978647639
- Missense
- Variant Prioritization Score for Impact Estimate 0.195
- REVEL 0.04
- CADD 3.65
- PolyPhen-2 0.01
- SIFT 0.27
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available