V38M (p.Val38Met) variant of CYP2C9 (Cytochrome P450 2C9)
V38M (p.Val38Met) in CYP2C9 (Cytochrome P450 2C9) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.13 / 1. The record also includes population frequency data and structural context.
V38M (p.Val38Met) variant details
- p.Val38Met
- NCI-TCGA Cosmic COSV5324
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.128
- REVEL 0.12
- CADD 9.88
- PolyPhen-2 0.48
- SIFT 0.00
- UniProt: Variant assessed as somatic; moderate impact.
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available