S51R (p.Ser51Arg) variant of CYP2C9 (Cytochrome P450 2C9)
S51R (p.Ser51Arg) in CYP2C9 (Cytochrome P450 2C9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data and structural context.
S51R (p.Ser51Arg) variant details
- p.Ser51Arg
- gnomAD rs1434716573
- Missense
- Variant Prioritization Score for Impact Estimate 0.214
- REVEL 0.02
- CADD 11.80
- PolyPhen-2 0.08
- SIFT 0.24
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available