S3Y (p.Ser3Tyr) variant of CYP2C9 (Cytochrome P450 2C9)
S3Y (p.Ser3Tyr) in CYP2C9 (Cytochrome P450 2C9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data and structural context.
S3Y (p.Ser3Tyr) variant details
- p.Ser3Tyr
- cosmic curated COSV53247
- ExAC rs774250598
- TOPMed rs774250598
- gnomAD rs774250598
- Missense
- Variant Prioritization Score for Impact Estimate 0.216
- REVEL 0.09
- CADD 2.16
- PolyPhen-2 0.01
- SIFT 0.02
- Most common in the African/African-American population (allele frequency 0.00031)
- Structural context available