S3F (p.Ser3Phe) variant of CYP2C9 (Cytochrome P450 2C9)
S3F (p.Ser3Phe) in CYP2C9 (Cytochrome P450 2C9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data and structural context.
S3F (p.Ser3Phe) variant details
- p.Ser3Phe
- cosmic curated COSV10729
- ExAC rs774250598
- TOPMed rs774250598
- gnomAD rs774250598
- Missense
- Variant Prioritization Score for Impact Estimate 0.219
- REVEL 0.10
- CADD 0.51
- PolyPhen-2 0.00
- SIFT 0.05
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available