P37A (p.Pro37Ala) variant of CYP2C9 (Cytochrome P450 2C9)
P37A (p.Pro37Ala) in CYP2C9 (Cytochrome P450 2C9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data and structural context.
P37A (p.Pro37Ala) variant details
- p.Pro37Ala
- ExAC rs764766385
- gnomAD rs764766385
- Missense
- Variant Prioritization Score for Impact Estimate 0.408
- REVEL 0.28
- CADD 22.30
- PolyPhen-2 0.95
- SIFT 0.00
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available