P35T (p.Pro35Thr) variant of CYP2C9 (Cytochrome P450 2C9)
P35T (p.Pro35Thr) in CYP2C9 (Cytochrome P450 2C9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data, published literature, and structural context.
P35T (p.Pro35Thr) variant details
- p.Pro35Thr
- gnomAD 10-94938785-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.345
- REVEL 0.17
- CADD 21.70
- PolyPhen-2 0.90
- SIFT 0.02
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available