P33L (p.Pro33Leu) variant of CYP2C9 (Cytochrome P450 2C9)
P33L (p.Pro33Leu) in CYP2C9 (Cytochrome P450 2C9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.48 / 1. The record also includes population frequency data and structural context.
P33L (p.Pro33Leu) variant details
- p.Pro33Leu
- gnomAD rs949431436
- Missense
- Variant Prioritization Score for Impact Estimate 0.478
- REVEL 0.39
- CADD 23.70
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available