L9P (p.Leu9Pro) variant of CYP2C9 (Cytochrome P450 2C9)
L9P (p.Leu9Pro) in CYP2C9 (Cytochrome P450 2C9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.49 / 1. The record also includes population frequency data, published literature, and structural context.
L9P (p.Leu9Pro) variant details
- p.Leu9Pro
- gnomAD 10-94938708-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.486
- REVEL 0.47
- MetaLR 0.59
- MetaSVM -0.35
- CADD 22.70
- PolyPhen-2 0.89
- SIFT 0.05
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available