L7F (p.Leu7Phe) variant of CYP2C9 (Cytochrome P450 2C9)
L7F (p.Leu7Phe) in CYP2C9 (Cytochrome P450 2C9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data and structural context.
L7F (p.Leu7Phe) variant details
- p.Leu7Phe
- ExAC rs763598557
- TOPMed rs763598557
- gnomAD rs763598557
- Missense
- Variant Prioritization Score for Impact Estimate 0.121
- REVEL 0.11
- CADD 10.70
- PolyPhen-2 0.05
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available