L57P (p.Leu57Pro) variant of CYP2C9 (Cytochrome P450 2C9)
L57P (p.Leu57Pro) in CYP2C9 (Cytochrome P450 2C9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.57 / 1. The record also includes population frequency data and structural context.
L57P (p.Leu57Pro) variant details
- p.Leu57Pro
- gnomAD rs1458065034
- Missense
- Variant Prioritization Score for Impact Estimate 0.574
- REVEL 0.61
- CADD 24.00
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 2.9e-05)
- Structural context available