L4F (p.Leu4Phe) variant of CYP2C9 (Cytochrome P450 2C9)
L4F (p.Leu4Phe) in CYP2C9 (Cytochrome P450 2C9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.05 / 1. The record also includes population frequency data and structural context.
L4F (p.Leu4Phe) variant details
- p.Leu4Phe
- cosmic curated COSV53250
- ExAC rs767472668
- TOPMed rs767472668
- gnomAD rs767472668
- Missense
- Variant Prioritization Score for Impact Estimate 0.0506
- REVEL 0.05
- CADD 0.00
- PolyPhen-2 0.00
- SIFT 0.15
- Most common in the Latino/Admixed American population (allele frequency 0.00018)
- Structural context available