L29F (p.Leu29Phe) variant of CYP2C9 (Cytochrome P450 2C9)
L29F (p.Leu29Phe) in CYP2C9 (Cytochrome P450 2C9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.10 / 1. The record also includes population frequency data, published literature, and structural context.
L29F (p.Leu29Phe) variant details
- p.Leu29Phe
- gnomAD 10-94938767-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.101
- REVEL 0.07
- CADD 12.10
- PolyPhen-2 0.11
- SIFT 0.02
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available