L19R (p.Leu19Arg) variant of CYP2C9 (Cytochrome P450 2C9)
L19R (p.Leu19Arg) in CYP2C9 (Cytochrome P450 2C9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
L19R (p.Leu19Arg) variant details
- p.Leu19Arg
- gnomAD rs1397713285
- Missense
- Variant Prioritization Score for Impact Estimate 0.269
- REVEL 0.15
- CADD 15.40
- PolyPhen-2 0.01
- SIFT 0.05
- Most common in the Non-Finnish European population (allele frequency 2.7e-06)
- Structural context available