L17F (p.Leu17Phe) variant of CYP2C9 (Cytochrome P450 2C9)
L17F (p.Leu17Phe) in CYP2C9 (Cytochrome P450 2C9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data and structural context.
L17F (p.Leu17Phe) variant details
- p.Leu17Phe
- gnomAD rs1401973837
- Missense
- Variant Prioritization Score for Impact Estimate 0.208
- REVEL 0.08
- CADD 0.08
- PolyPhen-2 0.00
- SIFT 0.52
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available