L14F (p.Leu14Phe) variant of CYP2C9 (Cytochrome P450 2C9)
L14F (p.Leu14Phe) in CYP2C9 (Cytochrome P450 2C9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data, published literature, and structural context.
L14F (p.Leu14Phe) variant details
- p.Leu14Phe
- gnomAD 10-94938724-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.314
- REVEL 0.20
- MetaLR 0.23
- MetaSVM -0.87
- CADD 11.00
- PolyPhen-2 0.40
- SIFT 0.05
- Population evidence available
- Structural context available
- Literature evidence available