L11P (p.Leu11Pro) variant of CYP2C9 (Cytochrome P450 2C9)
L11P (p.Leu11Pro) in CYP2C9 (Cytochrome P450 2C9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.50 / 1. The record also includes population frequency data and structural context.
L11P (p.Leu11Pro) variant details
- p.Leu11Pro
- TOPMed rs2031306271
- Missense
- Variant Prioritization Score for Impact Estimate 0.496
- REVEL 0.49
- CADD 22.50
- PolyPhen-2 0.67
- SIFT 0.00
- Most common in the East Asian population (allele frequency 5e-05)
- Structural context available