I45V (p.Ile45Val) variant of CYP2C9 (Cytochrome P450 2C9)
I45V (p.Ile45Val) in CYP2C9 (Cytochrome P450 2C9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data, published literature, and structural context.
I45V (p.Ile45Val) variant details
- p.Ile45Val
- gnomAD 10-94938815-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.145
- REVEL 0.02
- CADD 0.26
- PolyPhen-2 0.01
- SIFT 0.34
- Most common in the Non-Finnish European population (allele frequency 2.7e-06)
- Structural context available
- Literature evidence available