I45M (p.Ile45Met) variant of CYP2C9 (Cytochrome P450 2C9)
I45M (p.Ile45Met) in CYP2C9 (Cytochrome P450 2C9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data and structural context.
I45M (p.Ile45Met) variant details
- p.Ile45Met
- ExAC rs756322378
- TOPMed rs756322378
- gnomAD rs756322378
- Missense
- Variant Prioritization Score for Impact Estimate 0.198
- REVEL 0.05
- CADD 10.60
- PolyPhen-2 0.20
- SIFT 0.05
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available