I39T (p.Ile39Thr) variant of CYP2C9 (Cytochrome P450 2C9)
I39T (p.Ile39Thr) in CYP2C9 (Cytochrome P450 2C9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.46 / 1. The record also includes population frequency data, published literature, and structural context.
I39T (p.Ile39Thr) variant details
- p.Ile39Thr
- gnomAD 10-94938798-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.464
- REVEL 0.43
- CADD 22.80
- PolyPhen-2 0.85
- SIFT 0.02
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available