I39M (p.Ile39Met) variant of CYP2C9 (Cytochrome P450 2C9)
I39M (p.Ile39Met) in CYP2C9 (Cytochrome P450 2C9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data, published literature, and structural context.
I39M (p.Ile39Met) variant details
- p.Ile39Met
- gnomAD 10-94938799-T-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.328
- REVEL 0.23
- CADD 17.40
- PolyPhen-2 0.30
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available