G62S (p.Gly62Ser) variant of CYP2C9 (Cytochrome P450 2C9)
G62S (p.Gly62Ser) in CYP2C9 (Cytochrome P450 2C9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.53 / 1. The record also includes population frequency data and structural context.
G62S (p.Gly62Ser) variant details
- p.Gly62Ser
- TOPMed rs1564707283
- Missense
- Variant Prioritization Score for Impact Estimate 0.528
- REVEL 0.47
- CADD 25.30
- PolyPhen-2 0.98
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 9e-05)
- Structural context available