G46S (p.Gly46Ser) variant of CYP2C9 (Cytochrome P450 2C9)
G46S (p.Gly46Ser) in CYP2C9 (Cytochrome P450 2C9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.10 / 1. The record also includes population frequency data, published literature, and structural context.
G46S (p.Gly46Ser) variant details
- p.Gly46Ser
- gnomAD 10-94938818-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.104
- REVEL 0.09
- CADD 9.17
- PolyPhen-2 0.02
- SIFT 0.03
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available