G46R (p.Gly46Arg) variant of CYP2C9 (Cytochrome P450 2C9)
G46R (p.Gly46Arg) in CYP2C9 (Cytochrome P450 2C9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.08 / 1. The record also includes population frequency data, published literature, and structural context.
G46R (p.Gly46Arg) variant details
- p.Gly46Arg
- gnomAD 10-94938818-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.0834
- REVEL 0.08
- CADD 4.55
- PolyPhen-2 0.06
- SIFT 0.07
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available
- Literature evidence available