G40R (p.Gly40Arg) variant of CYP2C9 (Cytochrome P450 2C9)
G40R (p.Gly40Arg) in CYP2C9 (Cytochrome P450 2C9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.50 / 1. The record also includes population frequency data and structural context.
G40R (p.Gly40Arg) variant details
- p.Gly40Arg
- cosmic curated COSV10459
- TOPMed rs1364419386
- gnomAD rs1364419386
- Missense
- Variant Prioritization Score for Impact Estimate 0.498
- REVEL 0.42
- CADD 24.70
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 2.9e-05)
- Structural context available