G32S (p.Gly32Ser) variant of CYP2C9 (Cytochrome P450 2C9)
G32S (p.Gly32Ser) in CYP2C9 (Cytochrome P450 2C9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.51 / 1. The record also includes population frequency data, published literature, and structural context.
G32S (p.Gly32Ser) variant details
- p.Gly32Ser
- gnomAD 10-94938776-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.508
- REVEL 0.44
- CADD 24.40
- PolyPhen-2 1.00
- SIFT 0.01
- Most common in the East Asian population (allele frequency 5e-05)
- Structural context available
- Literature evidence available