F65L (p.Phe65Leu) variant of CYP2C9 (Cytochrome P450 2C9)
F65L (p.Phe65Leu) in CYP2C9 (Cytochrome P450 2C9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data and structural context.
F65L (p.Phe65Leu) variant details
- p.Phe65Leu
- gnomAD rs1176755716
- Missense
- Variant Prioritization Score for Impact Estimate 0.452
- REVEL 0.41
- CADD 22.90
- PolyPhen-2 0.39
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 2.7e-06)
- Structural context available