Y68C (p.Tyr68Cys) variant of CYP2C8 (Cytochrome P450 2C8)
Y68C (p.Tyr68Cys) in CYP2C8 (Cytochrome P450 2C8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data and structural context.
Y68C (p.Tyr68Cys) variant details
- p.Tyr68Cys
- ExAC rs751453931
- gnomAD rs751453931
- Missense
- Variant Prioritization Score for Impact Estimate 0.351
- REVEL 0.22
- CADD 23.90
- PolyPhen-2 0.98
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available