Y61D (p.Tyr61Asp) variant of CYP2C8 (Cytochrome P450 2C8)
Y61D (p.Tyr61Asp) in CYP2C8 (Cytochrome P450 2C8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.65 / 1. The record also includes population frequency data and structural context.
Y61D (p.Tyr61Asp) variant details
- p.Tyr61Asp
- gnomAD rs1380440546
- Missense
- Variant Prioritization Score for Impact Estimate 0.65
- REVEL 0.73
- CADD 25.90
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the South Asian population (allele frequency 0.00013)
- Structural context available