Y61C (p.Tyr61Cys) variant of CYP2C8 (Cytochrome P450 2C8)
Y61C (p.Tyr61Cys) in CYP2C8 (Cytochrome P450 2C8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.65 / 1. The record also includes population frequency data and structural context.
Y61C (p.Tyr61Cys) variant details
- p.Tyr61Cys
- ExAC rs748785700
- gnomAD rs748785700
- Missense
- Variant Prioritization Score for Impact Estimate 0.65
- REVEL 0.72
- CADD 27.30
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the South Asian population (allele frequency 2.3e-05)
- Structural context available