V8L (p.Val8Leu) variant of CYP2C8 (Cytochrome P450 2C8)
V8L (p.Val8Leu) in CYP2C8 (Cytochrome P450 2C8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.06 / 1. The record also includes population frequency data and structural context.
V8L (p.Val8Leu) variant details
- p.Val8Leu
- ExAC rs778470178
- gnomAD rs778470178
- Missense
- Variant Prioritization Score for Impact Estimate 0.0621
- REVEL 0.04
- CADD 2.57
- PolyPhen-2 0.01
- SIFT 0.57
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available