V76M (p.Val76Met) variant of CYP2C8 (Cytochrome P450 2C8)
V76M (p.Val76Met) in CYP2C8 (Cytochrome P450 2C8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.54 / 1. The record also includes population frequency data and structural context.
V76M (p.Val76Met) variant details
- p.Val76Met
- TOPMed rs1471056612
- Missense
- Variant Prioritization Score for Impact Estimate 0.537
- REVEL 0.50
- CADD 22.70
- PolyPhen-2 0.81
- SIFT 0.03
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available