V67M (p.Val67Met) variant of CYP2C8 (Cytochrome P450 2C8)
V67M (p.Val67Met) in CYP2C8 (Cytochrome P450 2C8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data and structural context.
V67M (p.Val67Met) variant details
- p.Val67Met
- ESP rs376132046
- ExAC rs376132046
- TOPMed rs376132046
- gnomAD rs376132046
- Missense
- Variant Prioritization Score for Impact Estimate 0.316
- REVEL 0.20
- CADD 10.20
- PolyPhen-2 0.33
- SIFT 0.04
- Most common in the African/African-American population (allele frequency 0.00019)
- Structural context available