V64M (p.Val64Met) variant of CYP2C8 (Cytochrome P450 2C8)
V64M (p.Val64Met) in CYP2C8 (Cytochrome P450 2C8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data and structural context.
V64M (p.Val64Met) variant details
- p.Val64Met
- TOPMed rs1416881603
- gnomAD rs1416881603
- Missense
- Variant Prioritization Score for Impact Estimate 0.411
- REVEL 0.53
- CADD 23.00
- PolyPhen-2 0.93
- SIFT 0.03
- Most common in the Middle Eastern population (allele frequency 0.00017)
- Structural context available