V60A (p.Val60Ala) variant of CYP2C8 (Cytochrome P450 2C8)
V60A (p.Val60Ala) in CYP2C8 (Cytochrome P450 2C8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data and structural context.
V60A (p.Val60Ala) variant details
- p.Val60Ala
- TOPMed rs1292038418
- gnomAD rs1292038418
- Missense
- Variant Prioritization Score for Impact Estimate 0.163
- REVEL 0.04
- CADD 1.55
- PolyPhen-2 0.01
- SIFT 0.71
- Most common in the Latino/Admixed American population (allele frequency 4.5e-05)
- Structural context available