T34S (p.Thr34Ser) variant of CYP2C8 (Cytochrome P450 2C8)
T34S (p.Thr34Ser) in CYP2C8 (Cytochrome P450 2C8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data and structural context.
T34S (p.Thr34Ser) variant details
- p.Thr34Ser
- TOPMed rs911527119
- gnomAD rs911527119
- Missense
- Variant Prioritization Score for Impact Estimate 0.259
- REVEL 0.07
- CADD 17.80
- PolyPhen-2 0.06
- SIFT 0.03
- Most common in the African/African-American population (allele frequency 4.8e-05)
- Structural context available