S115N (p.Ser115Asn) variant of CYP2C8 (Cytochrome P450 2C8)
S115N (p.Ser115Asn) in CYP2C8 (Cytochrome P450 2C8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data and structural context.
S115N (p.Ser115Asn) variant details
- p.Ser115Asn
- ExAC rs755391351
- TOPMed rs755391351
- gnomAD rs755391351
- Missense
- Variant Prioritization Score for Impact Estimate 0.403
- REVEL 0.30
- CADD 17.90
- PolyPhen-2 0.60
- SIFT 0.11
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available