S114F (p.Ser114Phe) variant of CYP2C8 (Cytochrome P450 2C8)
S114F (p.Ser114Phe) in CYP2C8 (Cytochrome P450 2C8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.10 / 1. The record also includes population frequency data and structural context.
S114F (p.Ser114Phe) variant details
- p.Ser114Phe
- ExAC rs752917521
- gnomAD rs752917521
- Missense
- Variant Prioritization Score for Impact Estimate 0.104
- REVEL 0.11
- CADD 2.75
- PolyPhen-2 0.01
- SIFT 1.00
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available