R26K (p.Arg26Lys) variant of CYP2C8 (Cytochrome P450 2C8)
R26K (p.Arg26Lys) in CYP2C8 (Cytochrome P450 2C8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data and structural context.
R26K (p.Arg26Lys) variant details
- p.Arg26Lys
- ExAC rs267602643
- gnomAD rs267602643
- Missense
- Variant Prioritization Score for Impact Estimate 0.197
- REVEL 0.04
- CADD 3.47
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available