R21S (p.Arg21Ser) variant of CYP2C8 (Cytochrome P450 2C8)
R21S (p.Arg21Ser) in CYP2C8 (Cytochrome P450 2C8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data and structural context.
R21S (p.Arg21Ser) variant details
- p.Arg21Ser
- ESP rs202131138
- ExAC rs202131138
- TOPMed rs202131138
- gnomAD rs202131138
- Missense
- Variant Prioritization Score for Impact Estimate 0.203
- REVEL 0.09
- CADD 6.89
- PolyPhen-2 0.02
- SIFT 0.05
- Most common in the Latino/Admixed American population (allele frequency 0.00033)
- Structural context available