R21G (p.Arg21Gly) variant of CYP2C8 (Cytochrome P450 2C8)
R21G (p.Arg21Gly) in CYP2C8 (Cytochrome P450 2C8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
R21G (p.Arg21Gly) variant details
- p.Arg21Gly
- ExAC rs757789288
- gnomAD rs757789288
- Missense
- Variant Prioritization Score for Impact Estimate 0.302
- REVEL 0.17
- CADD 23.20
- PolyPhen-2 0.03
- SIFT 0.00
- Most common in the South Asian population (allele frequency 8.1e-05)
- Structural context available