R21* (p.Arg21Ter) variant of CYP2C8 (Cytochrome P450 2C8)
R21* (p.Arg21Ter) in CYP2C8 (Cytochrome P450 2C8) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.61 / 1. The record also includes population frequency data and structural context.
R21* (p.Arg21Ter) variant details
- p.Arg21Ter
- ExAC rs757789288
- gnomAD rs757789288
- Stop Gained
- Variant Prioritization Score for Impact Estimate 0.611
- CADD 36.00
- Most common in the South Asian population (allele frequency 4.6e-05)
- Structural context available