R119K (p.Arg119Lys) variant of CYP2C8 (Cytochrome P450 2C8)
R119K (p.Arg119Lys) in CYP2C8 (Cytochrome P450 2C8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data and structural context.
R119K (p.Arg119Lys) variant details
- p.Arg119Lys
- cosmic curated COSV64878
- TOPMed rs2033591692
- Missense
- Variant Prioritization Score for Impact Estimate 0.228
- REVEL 0.12
- CADD 0.01
- PolyPhen-2 0.02
- SIFT 0.32
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available