Q44H (p.Gln44His) variant of CYP2C8 (Cytochrome P450 2C8)
Q44H (p.Gln44His) in CYP2C8 (Cytochrome P450 2C8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data and structural context.
Q44H (p.Gln44His) variant details
- p.Gln44His
- ExAC rs774695111
- gnomAD rs774695111
- Missense
- Variant Prioritization Score for Impact Estimate 0.413
- REVEL 0.32
- CADD 17.90
- PolyPhen-2 0.97
- SIFT 0.03
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available