P73L (p.Pro73Leu) variant of CYP2C8 (Cytochrome P450 2C8)
P73L (p.Pro73Leu) in CYP2C8 (Cytochrome P450 2C8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data and structural context.
P73L (p.Pro73Leu) variant details
- p.Pro73Leu
- cosmic curated COSV10652
- Ensembl rs778628526
- Missense
- Variant Prioritization Score for Impact Estimate 0.378
- REVEL 0.23
- CADD 22.70
- PolyPhen-2 0.53
- SIFT 0.04
- Most common in the Non-Finnish European population (allele frequency 9.9e-06)
- Structural context available