P73A (p.Pro73Ala) variant of CYP2C8 (Cytochrome P450 2C8)
P73A (p.Pro73Ala) in CYP2C8 (Cytochrome P450 2C8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data and structural context.
P73A (p.Pro73Ala) variant details
- p.Pro73Ala
- gnomAD rs1247362317
- Missense
- Variant Prioritization Score for Impact Estimate 0.369
- REVEL 0.22
- CADD 22.00
- PolyPhen-2 0.67
- SIFT 0.00
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available